A New Calcineurin Inhibitor, Pimecrolimus, Inhibits the Growth of Malassezia spp
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چکیده
منابع مشابه
A new calcineurin inhibitor, pimecrolimus, inhibits the growth of Malassezia spp.
Malassezia spp. are a component of the cutaneous microflora that colonizes lipid-rich areas, especially the head and neck, because the microorganisms require a lipid for its growth. An antiMalassezia-specific immunoglobulin E antibody is produced in patients with atopic dermatitis who have disrupted skin barrier function, while healthy subjects do not produce the immunoglobulin E antibody. In a...
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Atopic eczema is a chronic inflammatory skin disorder with a relapsing and remitting course. For many decades,topical corticosteroids have been the mainstay therapy for atopic dermatitis. After the introduction of calcineurin inhibitors as a corticosteroid-free alternative, there were high expectations. After the black box warning from the FDA regarding the potential theoretical risk for develo...
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BACKGROUND Malassezia pachydermatis is a yeast of importance in both veterinary and human medicine. AIMS To know if M. pachydermatis grow on mycological media with high concentrations of gentamycin. METHODS Twenty M. pachydermatis strains were streaked on Sabouraud Dextrose Agar plates with different concentrations of gentamycin. RESULTS All isolates were inhibited when high concentration...
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Malassezia spp. is a genus of lipophilic yeasts and comprises the most common fungi on healthy human skin. Despite its role as a commensal on healthy human skin, Malassezia spp. is attributed a pathogenic role in atopic dermatitis. The mechanisms by which Malassezia spp. may contribute to the pathogenesis of atopic dermatitis are not fully understood. Here, we review the latest findings on the ...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2006
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.00687-06